PT - JOURNAL ARTICLE AU - Dragana Jovanovic AU - Nevana Secan AU - Zafir Murtezani AU - Milan Rancic AU - Vesna Kacar-Kukric AU - Marta Velinovic AU - Ana Tepavac AU - Evica Budisin AU - Zoran Andric AU - Nevena Vukobradovic Djoric TI - Analysis of clinicopathological characteristics of 982 lung cancer patients and subsequent treatment - Epidemiology study DP - 2013 Sep 01 TA - European Respiratory Journal PG - P4535 VI - 42 IP - Suppl 57 4099 - http://erj.ersjournals.com/content/42/Suppl_57/P4535.short 4100 - http://erj.ersjournals.com/content/42/Suppl_57/P4535.full SO - Eur Respir J2013 Sep 01; 42 AB - The purpose of the survey was the analysis of clinicopathological features of lung cancer patients in Serbia and subsequent treatment approach.Method: the data were collected based on specific questionnaire at 4 major centers in Serbia.Results. Out of 982 patients (pts), NSCLC was diagnosed in 80% (789), 71.6% (679) in stage IIIb and IV. Most common histological subtype was adenocarcinoma (46%), followed by squamous cell carcinoma (44%). Neodjuvant therapy was applied in 8% (67pts), while 19% (153pts) were operated - 64% (98) of operated patients recieved adjuvant chemotherapy. Among IIIb/IV NSCLC patients, 91% (511) recieved 1st line chemotherapy, platinum/etoposide (51%) and platinum/gemcitabine (45%) most frequently applied regimens. Second line chemotherapy was given to 27% (136) of 1st line treated patients. Third line chemotherapy was applied in 22% (29) of 2nd line treated patients.Conclusions. This is the largest series of lung cancer patients in Serbia, analized by both, patient characteristics and treatment. Compared to previous similar NSCLC analysis in 2009, the number of NSCLC patients is obviously increasing (1.5% per year). Rate of adenocarcinoma is also increasing (41% in 2009 vs 45% in 2011). Regarding treatment options, there is no significant difference.