RT Journal Article SR Electronic T1 Post-extubation outcomes in a tertiary referral cardio-thoracic intensive care unit (CICU) JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2432 VO 42 IS Suppl 57 A1 Charlotte Pereira A1 Martin Rooms A1 Rakhee Shah A1 Layla Meshykhi A1 Grainne Gallagher A1 Kat Elliott A1 Sunny Kaul YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/P2432.abstract AB Extubation failure is associated with increased length of stay (LOS) and higher mortality rate. There is little published data (Thille et al. Crit Care Med 2011; 39:2612-2618) on modifiable risk factors.Aim: Record outcomes of all patients extubated in a tertiary referral CICU and identify risk factors predicting poorer outcomes.Hypothesis: Re-admissions, re-intubations and tracheostomies will be associated with poorer outcomes.Method/Design & Setting: Prospective 1-year observational study in a 25 bedded level 3 CICU facility. Data retrieved from paperless patient record system and patients followed up till discharge or death. The first 6 months data is reported here.Results: Total number of admissions is 650, (43 re-admissions); 70 % male, mean age 64 years (SD 15). Indications for admission: post-cardiac surgery (71%) transplant (8%) ventricular assist device insertion (4.5%) thoracic surgery (3.5%) cardiology (12%) thoracic medicine (1%). Table 1 shows the outcomes.View this table:Table 1Conclusion: This is the first known report of post-extubation outcomes in a CICU setting. Re-intubation, re-admission, tracheostomy and higher baseline serum creatinine (Cr) are all associated with poor outcomes. Further data collection is underway to identify cardio-respiratory modifiable factors and report 1 year LOS and mortality.