TY - JOUR T1 - Comparison between dual-energy computed tomography and standard lung perfusion scintigraphy in preoperative evaluation of lung cancer patients JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P2880 AU - Johannes Mueller AU - Helene Vogelsinger AU - Florian Augustin AU - Wolfgang Recheis AU - Tobias De Zordo AU - Gudrun Feuchtner AU - Christian Kaehler Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P2880.abstract N2 - Background: In the pre-operative assessment of lung cancer patients functional evaluation of operability is a crucial step. It includes, apart from spirometry, measurement of diffusion capacity and exercise testing, split function studies by means of lung perfusion scintigraphy. Using this approach it is possible to predict postoperative lung function and therefore assess resection limit and operability. As computed tomography (CT) is essential for pre-operative evaluation in every patient, a recently advanced CT-protocol, the so called dual-energy computed tomography (DECT), by which lung tissue perfusion gets visible, might be a new and better alternative to radioactive scintigraphy.Objectives: To compare calculated percentage values for perfused lung tissue, as measured on the one hand by lung perfusion scintigraphy and on the other hand gathered by DECT.Methods: Seven patients were included in this pilot project. All patients had to undergo lung perfusion scintigraphy, as well as dual-energy computed tomography a few days before surgery. Lung function testing and assessment of diffusion capacity was performed in all patients preoperatively.Results: Patients (mean age 61±8 yrs) were investigated by scintigraphy and DECT. Split studies revealed no significant difference in calculated percentages for lung perfusion between both methods (p>0.05). Values for the FEV1 ppo did not differ between scintigraphy or DECT results which served as basis for calculation.Conclusion: There is no significant divergence between the use of dual-energy CT and lung perfusion scintigraphy for pre-operative evaluation of lung cancer patients. ER -