RT Journal Article SR Electronic T1 Smoking cessation in the last decade in an Italian prospective study JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP 3345 VO 42 IS Suppl 57 A1 Giuseppe Verlato A1 Giang Nguyen A1 Pierpaolo Marchetti A1 Lucia Cazzoletti A1 Francesca Locatelli A1 Marcello Ferrari A1 Alessandro Fois A1 Pietro Pirina A1 Roberto de Marco YR 2013 UL http://erj.ersjournals.com/content/42/Suppl_57/3345.abstract AB Background: Smoking trends in Italy have been addressed mainly by repeated cross-sectional surveys or retrospective studies.Objective: To prospectively assess cumulative incidence and determinants of smoking cessation among Italian smokers during the last decade.Methods: 1390 current smokers aged 20-46 years were identified in 1998-2000 in two centres participating in ISAYA (Italian Study on Asthma in Young Adults): Verona in Northern Italy and Sassari in Sardinia. These subjects were contacted again in 2008-2009 and 684 answered a screening questionnaire; of note response percentage (49.2%) in current smokers was significantly lower than that recorded among never and past smokers (57.0% and 53.9% respectively). After eliminating 56 subjects with missing or contradictory response on smoking habits, 628 subjects were left for the analysis.Results. After a follow-up period of 9.5±0.6 years (mean±SD) 219 subjects (34.9%) had stopped smoking. This proportion was similar in both sexes (35.7% in men, 33.9% in women) and was not significantly affected by either birth cohort or occupation. Quit ratio was higher in Verona (37.4%) than in Sassari (30.4%) (p=0.082) and in people smoking 11-40 cigarettes/day at baseline (39.8%) than in people smoking 1-10 cigarettes/day (29.4%) (p=0.007). Asthma at baseline was associated with an increase in quit ratio (54.2% vs 34.1%; p=0.050), while nasal allergies and chronic bronchitis were not. Only smoking intensity was a significant predictor of smoking cessation in a multivariable logistic regression model.Conclusion. About one third of current smokers quitted smoking over a ten-year period. The main predictor of smoking cessation was smoking intensity.