TY - JOUR T1 - Unusual metastases in lung cancer JF - European Respiratory Journal JO - Eur Respir J VL - 42 IS - Suppl 57 SP - P4530 AU - Othmen Neffati AU - Ines Akrout AU - Hanene Smadhi AU - Leila ElFekih AU - Tawaddod Khmis AU - Dorra Greb AU - Hela Hassen AU - Hajer BenAbdelghaffar AU - Souraya Fenniche AU - Mohamed Lamine Megdiche Y1 - 2013/09/01 UR - http://erj.ersjournals.com/content/42/Suppl_57/P4530.abstract N2 - Introduction: Common sites of lung cancer metastases are liver, bone, brain and adrenal. However, few other locations have been described in the literature such as cutaneous, muscular, renal, pancreatic and cardiac.Purpose: Illustrate the unusual locations of lung cancer metastases.Methods: A retrospective study conducted during a period of five years including the patients with lung cancer and unusual metastatic sites.Results: Eleven patients (9men and 2women) with a mean age of 52 years [32-70]. The mean duration of symptoms was 2.5 months. Histological types were: adenocarcinoma (7 cases), a small cell carcinoma (2 cases), squamous cell carcinoma(1 case) and a large cell cancer(1case). Two patients had more than one metastasis (two different sites). There were cutaneous metastases (4cases), renal (4cases), pancreatic (2cases), ovarian (1case), cardiac (1case) and musclular (1case). Metastasis had revealed lung cancer in one case. The histological diagnosis of lung cancer was confirmed by bronchial biopsy (6cases) percutaneous CT guided biopsy (1case) mediastinoscopy (1case) and the biopsy of ovarian site (1case). Chemotherapy was given in nine cases and palliative treatment in two cases. The evolution was rapidly progressive in all patients. The median survival was 4 months.Conclusion: Unusual metastases in lung cancer have a poor prognosis because of a late diagnosis. These are often asymptomatic and discovered in radiology. Therefore, their screening should be systematic. ER -