%0 Journal Article %A Guitti Pourdowlat %A Farin Rashid Farokhi %T Pleural effusion in hemodialysis patients with chronic kidney disease %D 2012 %J European Respiratory Journal %P P580 %V 40 %N Suppl 56 %X Background: Uremic patients are susceptible to many causes of pleural effusions. Moreover, uremia directly creates a kind of exudative pleural effusion. Uremic pleuritis has been introduced as a clinicipathologic entity for the past four decades. However, knowledge of pathogenesis, clinical course and management of this complication is still limited.Materials and methods: In this study, 76 chronic hemodialysis patients with pleural effusion admitted in hospital between June 2005 and May 2011, and evaluated for the etiology of pleural effusion and associated clinicopathological findings. Statistical tests of Chi square, ANOVA and Kruskal Wallis were used to compare patient's data with the most common etiologies of pleural effusion.Results: Parapneumonic effusion (23.7%), uremic pleuritis(23.7%) CHF (19.7%) volume overload (6.6%) tuberculosis (6.6%) and malignancy (5.4%) were the most common causes of pleural effusion. There was not any significant difference in the frequency of presenting symptoms such as; Dyspnea, cough, weight loss, anorexia, chest pain and fever, in patients with CHF and uremic pleuritis. Moreover, pleural Adenosine Deaminase levels were not different in patients with tuberculosis, uremic pleuritis, parapneumonic effusion and CHF.Conclusion: Infectious disease including parapneumonic effusion and tuberculosis can be the most common causes of pleural effusion in hemodialysis patients. This study showed that some inflammatory pleural reactions such as increase in pleural leukocyte count and ADA may be attenuated in hemodialysis patients. %U https://erj.ersjournals.com/content/erj/40/Suppl_56/P580.full.pdf