PT  - JOURNAL ARTICLE
AU  - Eid Almutairy
AU  - Naseer Alshekaily
AU  - Basha Khan
AU  - Waleed Saleh
AU  - Imran Nizami
TI  - Prevalence and outcome of donor transmitted Acinetobacter baumannii in lung transplant patients in Saudi Arabia
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P2448
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P2448.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P2448.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Background: Donor transmission of organism to the lung transplant recipient is a known entity. The shortage of ideal donors and the increasing pool of lung transplant candidates is increasing the pressure to utilize extended donors. Large number of our donors have been on ventilator for extended period of time, hence bringing the risk of nosocomial infections. We describe our experience with acinetobacter baumannii pneumonia in the lung transplant patients.Methods: Retrospective chart review of all the patients transplanted between March 2010 and August 2011. The patients with acinetobacter baumannii pneumonia transmitted from donors were compared to those not affected by such infections. The primary graft dysfunction, duration of mechanical ventilation, ICU length of stay, acute kidney injury and mortality were measured.Results: A total of 18 patients underwent lung transplant during this period. There were 8 male and 10 female recipients. A total of 6 patients developed acinetobacter baumannii multidrug resistant pneumonia. The primary graft dysfunction was seen in 100 % vs. 91 %; median duration of mechanical ventilation was 14 vs. 2; median ICU length of stay was 19.5 vs. 6.5; acute kidney injury was 33 % vs. 41 % and mortality was 33 % vs. 8 % in the acinetobacter vs. non acenetobacter group.Conclusion: Isolation of acinetobacter baumannii in respiratory culture from donor lungs was associated with worse outcomes in transplanted patients as compared to donor lungs without acinetobacter. Antibiotic coverage should be tailored to include this organism when suspected as soon as possible. Also a method for rapid identification of acinetobacter baumannii is needed.