PT  - JOURNAL ARTICLE
AU  - María Guadalupe Silveira
AU  - Patricia Chang-Macchiu
AU  - Cecilia Pérez
AU  - Sergi Martí
AU  - María-Antonia Ramón
AU  - Mercedes Pallero
AU  - Esther Rodriguez
AU  - Cristina Berastegui
AU  - Antonio Román-Broto
AU  - Jaume Ferrer
TI  - Home mechanical ventilation in lung transplant patients
DP  - 2013 Sep 01
TA  - European Respiratory Journal
PG  - P2459
VI  - 42
IP  - Suppl 57
4099  - http://erj.ersjournals.com/content/42/Suppl_57/P2459.short
4100  - http://erj.ersjournals.com/content/42/Suppl_57/P2459.full
SO  - Eur Respir J2013 Sep 01; 42
AB  - MethodsWe performed an observational study of LT patients that required HMV in a single center from 1991 to 2012. We collected baseline patient's characteristics when HMV was started. Follow-upuntil HMV withdrawal or death was analyzed by Kaplan-Meier survival curves.ResultsSeventeen out of 642 LT patients required HMV (2.6%); mean age 46±16 years, 15 double-LT.Indications (Table): 10 diaphragm paralysis (DP, 59%), 8 support to weaning; 6 chronic allograft dysfunction (CAD, 35%); and 1 bronchial stenosis/malacia (6%). Airway access: 16 non-invasive, 1 tracheostomy. Outcomes: HMV could be discontinued in 90% DP patients (median 5.5 months, p25-75 3.8-6.9). In CAD patients, 3 died (at 1.5, 2 and 28 months) and 3 are still using HMV at 6, 13 and 26 months.View this table:Home mechanical ventilation in lung transplant patientsConclusions- Diaphragm paralysis with weaning failure and chronic allograft dysfunction with respiratory failure could be HMV indications in LT recipients.- In diaphragm paralysis patients, recovering phrenic function may allow ventilation withdrawal in most patients.