RT Journal Article
SR Electronic
T1 Acute lower respiratory tract infection and vitamin D status in children
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4121
VO 40
IS Suppl 56
A1 Ayse Tana Aslan
A1 Tugba Eyuboglu
A1 Ozlem Gulbahar
A1 Secil Ozkan
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P4121.abstract
AB Childhood acute lower respiratory infection (ALRI) is one of the most common reason for morbidity and mortality especially in developing countries. Predisposing factors include season, nutrition, suboptimal immunization, lower socioeconomic status, prematurity, underlying disease, tobacco exposure and vitamin D deficiency.Vitamin D deficiency is the 25(OH)D levels below < 20 ng/ml, whereas vitamin D insufficiency is defined as 25(OH)D 21-30 ng/ml. In a study in Turkey the incidence of vitamin D deficiency in children was found 8% and insufficiency 25,5 %.In this study we aimed to describe vit D status in children with lower respiratory infection. Between November 2010 and February 2011 63 children with acute lower respiratory infection between 0.5-5 years of age and 59 age matched children without respiratory symptoms were enrolled in the study. Both study and control groups received vitamin D prophylaxis for one year and they have no predisposing factors for ALRI. Vitamin D status of children with acute lower infection (mean 34,9 ng/ml) were compared with children without ALRI (mean 37,2 ng/ml). No difference was found between the patient and the control group (p=0,38). In the patient group 17 patients diagnosed to have ALRI again after February 2011 – after one year period. In terms of ALRI recurrence, statistically significant difference was found between vitamin D status normal and insufficient patients (p= 0,003).In conclusion although there was no association between vitamin D status and childhood ALRI, significant association was found between vitamin D status and ALRI recurrence. Larger serial studies are needed for precise results.