TY - JOUR T1 - Assessment of fissure integrity for decision-making in valve treatment of emphysema: Preliminary results JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P679 AU - Hugo Oliveira AU - Rafael Rambo AU - Silvia Oliveira AU - Enio Valle AU - Amarilio Macedo-Neto Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P679.abstract N2 - Objective. To investigate if fissure integrity can determine collateral ventilation and guide endobronchial valve (EBV) treatment of emphysema.Method. The study is underway. We employ the Apollo software (VIDA Diagnostics) for treatment planning, and developed a visual fissure integrity score using a sagittal view through pre-treatment CT scans, to determine which % of the fissure was visible: <70% (incomplete); 70-90% (partial); >90% (complete). Before treatment, collateral ventilation is measured with Chartis (Pulmonx Inc., a balloon catheter inserted into the airway + console showing airflow, pressure, and resistance).Preliminary results:View this table:Two cases showing correlation between fissure integrity and collateral ventilationCase 1 was successfully treated based on fissure completeness.Case 2 received an additional valve in a neighboring segment after detection of collateral ventilation.Conclusion. Fissure integrity could be a reliable indicator of collateral ventilation and support EBV treatment of homogeneous emphysema. ER -