RT Journal Article
SR Electronic
T1 Lung cancer patients in TB hospital: Factors associated with diagnostic delay
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3143
VO 40
IS Suppl 56
A1 Zhanna Laushkina
A1 Pavel Filiimonov
A1 Elena Pushkareva
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P3143.abstract
AB The delay of diagnostics worsens prognosis of disease.The purpose. To define factors, associated with a delay of lung cancer diagnostics.Materials and methods. An analysis of waiting times for 31 patients with lung cancer was undertaken. Males 65 %, villagers 61 %, mean age 55 ± 14 yrs. Clinical, radiological, laboratory data of all admitted patients were collected. The period from the disease manifestation up to making a hospital diagnosis was 106 ± 68 days, patient delay - 25 ± 30 days. 39 % of patients were previously treated of an assumed pneumonia before hospitalization in TB hospital. All patients have been hospitalized with wrong diagnosis "pulmonary TB", a principal cause - misinterpretation of chest radiogram. 48 % of patients up to making a hospital diagnosis received antituberculous treatment. 55 % of patients - smokers.Results. Factors associated with increase of diagnostic delay: acute disease beginning (OR 0,34, p=0,03), absence of hematological changes (OR 0,23, p=0,01), nonspecific microbial growth in sputum (OR 0,1, p=0,003). Factors, associated with decrease of a diagnostic delay – old age (OR 2,7, p=0,034), low body weight (OR 2,4, p=0,038), lost of appetite (OR 3,7, p=0,006), dyspnea (OR 3,4, p=0,002), leukocytosis (OR 2,5, p=0,03), ESR acceleration (OR 3,3, p=0,007), lymphopenia (OR 2,5, p=0,043), eosinophilia (OR 3,3, p=0,01), spherical opacity patterns on chest radiogram (OR 5,9, p=0,000), pleural exudates (OR 11,7, p=0,000), presence of atypical cells in sputum (OR 46, p=0,000), biopsy performed (OR 10,5, p=0,000).Conclusion. The results would allow to optimize the diagnostic approaches to such a patients.