RT Journal Article SR Electronic T1 Ventilation parameters in asthmatic children after one week at 1400 meters altitude JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P875 VO 40 IS Suppl 56 A1 Alessandro da Ponte A1 Annarita Tullio A1 Bruno Grassi A1 Mario Canciani YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P875.abstract AB Introduction and backgroundBronchial asthma prevalence is increasing. Many triggers are known but little about protective factors.Aims and objectivesTo find out whether 1400 meters altitude could modify ventilation parameters, NO (Nitric Oxide) concentration and clinical symptoms in 13 children after a week of uncontrolled physical activity.MethodsThirteen asthmatic children were evaluated at arrival and departure from a mountain resort for: FVC, FEV1, FEF 25-75 and exhaled NO concentration. Unscheduled physical activity were encouraged for eight hours daily.ResultsAll the children showed improvement of FVC, FEV1, FEF 25-75.View this table:Main Ventilation Parameters and NO concentationConclusions: after a week permanence at 1400 meters resort all subjects showed an improvement in ventilation parameters, together with no episode of asthma exacerbations. This study suggests that physical activity in an healthy environment can be safe and feasible for asthmatic children.