RT Journal Article
SR Electronic
T1 Sarcoidosis in Sao Paulo, Brazil: Clinical, tomographic and lung functions data from 72 patients
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3683
VO 40
IS Suppl 56
A1 Agostinho Hermes Medeiros-Neto
A1 Fabiola Gomes Rodrigues
A1 Carlos Roberto Ribeiro Carvalho
A1 Ronaldo Adib Kairalla
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P3683.abstract
AB As part of major study on prevalence of pulmonary hypertention in outpatients with sarcoidosis, a sample of patients underwent prospective clinical, tomographic and lung function evaluation. Objective: to describe clinical, imaging and lung function data of 72 consecutive patients with sarcoidosis. Methods: Between September 2008 and September 2010, 72 consecutive patients underwent evaluation in a prospective fashion. All patients underwent clinical interview, chest radiography, high resolution computerized tomography and lung function tests (spirometry, lung volumes by pletysmography and carbon monoxide diffusion DLCO). Results: Clinical characterization: 69.4% female, age 54.5 ± 12.6. Smoking status: 63% non-smokers. Disease duration was 9.2 ± 6.1 years. Pulmonary involvement was the most prevalent (91.7%), followed by lymph nodes and cutaneous envolvement. Number of extra pulmonary organ involvement was 1.6 ± 1.1 organ per patient. Near 62% of patients had interrupted working activities for more than two weeks due to sarcoidosis morbidity. Up to 26% of patients had used imunossupressive drugs for sarcoidosis, and 81.6% had taken corticosteroids. Three patients (4.1%) used oxygen therapy. Scadding stage: 28.2% stage 0; 16.9% stage 1; 23.9% stage 3; 15.5% stage 3 and 15.5% stage 4. Lung function data: FVC 85.9 ± 16.5%, VEF1 82.7 ± 15.1%, VEF/CVF 96.8 ± 8.8%; TLC 89.7 ± 14.9%, RV 103.1 ± 26.1%; DLCO 76.7 ± 17,7%. Tomographic findings: parenchymal involvement in 64.5% of patients. Large (>1.5 cm) lymph nodes in 33.9%. Conclusion: our sample of patients prospectively evaluated is quite similar to other series of outpatiets described.