@article {TargowskaP3818, author = {Monika Targowska and Robert Plywaczewski and Luiza Jonczak and Anna Czyzak-Gradkowska and Pawel Sliwinski}, title = {Glucose metabolism abnormalities in obstructive sleep apnoea (OSA) patients}, volume = {40}, number = {Suppl 56}, elocation-id = {P3818}, year = {2012}, publisher = {European Respiratory Society}, abstract = {Obstructive sleep apnoea may be recognized a risk factor of diabetes type 2. The aim of this study was to assess an oral glucose tolerance test (OGTT) in OSA subjects. We studied 305 OSA pts [234 males (76.7\%) and 71 females (23.3\%)], mean age = 56.4{\textpm}10.9 years, AHI = 42.2{\textpm}20.9, BMI = 33.1{\textpm}5.5 kg/m2). Impaired glucose tolerance (IGT) (plasma level >= 140 mg\% after 2 hours of administration 75 g glucose) was found in 81 subjects (26.6\%). Among them in 13 patients (4.3\%) OGTT allowed to diagnose diabetes (glucose >= 200 mg\%). Comparison of OSA patients with- and without IGT is shown in the table.View this table:Multiple linear regression analysis confirmed significant correlation between AHI ({\ss}=0.13, p=0.04), age ({\ss}=0.21, p=0.0002), min SaO2 ({\ss}= -0.18, p=0.035) and IGT.Logistic regression revealed significant correlation between abnormal results of OGTT and arterial hypertension.Conclusions: Impaired glucose tolerance was frequent in OSA subjects (near 30\%). OSA patients with IGT were older and had higher prevalence of arterial hypertension. HBA1C is a good parameter of glucose metabolism in OSA patients.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/40/Suppl_56/P3818}, eprint = {https://erj.ersjournals.com/content/40/Suppl_56/P3818.full.pdf}, journal = {European Respiratory Journal} }