@article {MoraisP3606, author = {Anna Morais and MariaCecilia Maiorano and Juliana Puka and Caio Fernandes and Frederico Fernandes and Gustavo Prado and Teresa Takagaki}, title = {CT-guided biopsy of lung lesions: Experience of an oncology center in Brazil}, volume = {40}, number = {Suppl 56}, elocation-id = {P3606}, year = {2012}, publisher = {European Respiratory Society}, abstract = {Introduction: Computed tomography (CT) guided lung biopsy is widely accepted as an effective and safe diagnostic procedure for accessing thoracic lesions. Aims: To present the experience of an oncology center in Brazil in the use of CT-guided lung biopsy and describe its effectiveness and complications. Materials and methods: A retrospective analysis of medical records from outpatients attending routine consultations at Pulmonary Division of S{\~a}o Paulo State Cancer Institute (S{\~a}o Paulo, Brazil), who underwent transthoracic biopsy between December 2010 and November 2011 was conducted. Descriptive analysis of patients{\textquoteright} characteristics, lesions{\textquoteright} aspects, procedure techniques, diagnostic yield and complications was performed. Subgroup analysis was carried out to access differences between complicated and non-complicated procedures. Predictors of complications identified in univariate analysis were submitted to logistic regression to explore their significance as independent risk factors. Results: 71 subjects were submitted to CT-guided lung biopsy. Results were diagnostic in 60 cases (84.5\%). Lesions were malignant in 55 (91.6\%) and benign in 4 cases. Overall complication rate was 22\% and included 14 pneumothorax (19.7\%) and 2 hemothorax (2.8\%). Chest drainage was necessary in 4 cases (5.6\%). A statistically significant correlation was found between lesion diameter and complication. Smaller lesions were associated with higher rates of complications (OR 9.82, for first quartile vs others). Conclusions: CT-guided lung biopsy resulted in a high diagnostic yield with an acceptable rate of non-severe complications, being pneumothorax the most frequent. Small lesions were more prone to complicate.}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/40/Suppl_56/P3606}, eprint = {https://erj.ersjournals.com/content/40/Suppl_56/P3606.full.pdf}, journal = {European Respiratory Journal} }