RT Journal Article
SR Electronic
T1 The impact of MRC classification on daily physical activity and physical health-related quality of life in mild to moderate COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P4387
VO 40
IS Suppl 56
A1 Hans Van Remoortel
A1 Miek Hornikx
A1 Heleen Demeyer
A1 Kristien De Bent
A1 Erica Balligand
A1 Laurence Vrancken
A1 Chris Burtin
A1 Daniel Langer
A1 Marc Decramer
A1 Rik Gosselink
A1 Wim Janssens
A1 Thierry Troosters
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P4387.abstract
AB Dyspnea, reduced physical activity (PA) and impaired health-related quality of life (HRQL) are common features in COPD. This study aimed to investigate the impact of dyspnea on PA and HRQL in mild/moderate COPD.Fifty-three subjects with COPD and 60 smoking controls were recruited. Medical Research Council (MRC) classified patients by symptoms of dyspnea. The SenseWear Armband was worn for 7 days and time spent in at least moderate intense PA and amount of steps served as PA estimates. HRQL was assessed by the SF-36 physical functioning score and the EQ5D general health VAS score.View this table:Table 1. Patient characteristics.Moderate intense PA was significantly reduced in MRC1 COPD compared to MRC1 smokers and tended to be lower versus MRC0 COPD (p=0.10). A trend for reduced daily steps in MRC1 COPD was observed versus MRC1 smokers and MRC0 COPD, p=0.09. MRC1 COPD reported reduced physical functioning and VAS scores versus MRC1 smokers and MRC0 COPD (70±19 vs 81±13 vs 91±7 for physical functioning, p<0.01 and 71±12 vs 77±7 vs 81±10 for VAS score, p<0.05).PA levels are reduced in symptomatic patients with mild to moderate COPD. MRC classification, as proposed by the new GOLD guidelines, is useful in identifying reductions in PA and (physical) HRQL, even in the early stages of COPD.