RT Journal Article SR Electronic T1 Preference, satisfaction and critical errors with Genuair® and HandiHaler® in patients with COPD JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2177 VO 40 IS Suppl 56 A1 Job van der Palen A1 Thomas Ginko A1 Axel Kroker A1 Paul van der Valk A1 Martijn Goosens A1 Laura Padulles A1 Beatriz Seoane A1 Ludmyla Rekeda A1 Esther Garcia Gil YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P2177.abstract AB Introduction: Treatment outcomes in COPD depend on patient preference and satisfaction with their inhaler and inhaler technique. Patients often use their inhaler incorrectly, making critical errors that mean they get no drug or a suboptimal dose, leading to under-treatment of their disease.Aims: To investigate patient preference, satisfaction and critical errors with Genuair® vs HandiHaler® after 2 weeks of daily use.Methods: This was an open-label, randomised, cross-over, multicentre study in patients with COPD. Patients inhaled placebo through Genuair® and HandiHaler® daily for 2 weeks in addition to their current medication. The primary endpoint was the percentage of patients who preferred Genuair® after 2 weeks. Additional endpoints for each inhaler were overall patient satisfaction on a scale of 1 (very dissatisfied) to 5 (very satisfied), percentage of patients making ≥1 critical errors, and willingness to continue using each inhaler rated from 0 (not) to 100 (definitely). Data were analysed using Mainland-Gart's test or ANOVA.Results: The ITT population included 105 patients. Assessments at 2 weeks are shown in the table.View this table:Conclusions: Genuair® was associated with higher patient preference, satisfaction and fewer critical inhaler errors vs HandiHaler®.This study was supported by Almirall S.A., Barcelona, Spain, and Forest Laboratories, Inc., New York, USA.