RT Journal Article SR Electronic T1 An analysis for neuro-psychiatric symptoms in stable COPD patients and to assess for their correlation with patients' characteristics and BODE index JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P2291 VO 40 IS Suppl 56 A1 Prem Parkash Gupta A1 Hitesh Khurana A1 Sachin Bansal A1 Dipti Agarwal YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P2291.abstract AB Background: COPD is known to have significant extrapulmonary involvement that contributes to COPD morbidity.Aims: To assess neuro-psychiatry symptoms in stable COPD patients using Symptom Check List 80 Questionnaire [SCL-80] and to seek for any correlation between these symptoms and COPD severity.Methods: We included 200 stable COPD patients and 50 healthy volunteers (HV). The COPD subjects had a smoking history > 20 pack years. SCL-80 was used to assess neuro-psychiatric symptoms under 9 subscales (table - 1).Results: The age of subjects in HV group was 59.76 ± 7.21 year, and of those in COPD Group was 61.37 ± 7.4 year. 138 COPD patients (69%) had neuro-psychiatric symptom(s) detected using SCL-80. The SCL-80 scores are shown in table - 1.View this table:Table - 1Age, duration of illness, smoking pack years, MMRC dyspnea and BODE index scores had positive correlations with SCL-80 scores. FEV1 and distance walked in six minute had inverse correlations with SCL-80 scores.Conclusions: 69% stable COPD patients had neuro-psychiatric symptom(s) detected using SCL-80, and the SCL-80 scores had significant correlations with age, smoking pack years, duration of illness and BODE index variables.