PT  - JOURNAL ARTICLE
AU  - Javier de Miguel Díez
AU  - Jorge Chancafe Morgan
AU  - Pilar Carrasco Garrido
AU  - Valentín Hernández Barrera
AU  - Paula Rodríguez Rodríguez
AU  - Luis Puente Maestu
AU  - Angel Gil de Miguel
AU  - Rodrigo Jiménez García
TI  - Hospitalizations from pandemic influenza (pH1N1) infections among patients with COPD in Spain
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P3991
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P3991.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P3991.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Objectives: We describe and analyze the clinical characteristics and outcomes for all persons suffering COPD who were hospitalized with laboratory confirmed pH1N1 infection in Spain in 2009.Methods: This is an observational retrospective study using hospitalization data collected by the Spanish National Hospital Discharge Database. We selected all admissions with diagnosis ICD-9-CM code 488.1 (pH1N1). Discharges were grouped, according to the presence or not of COPD. The outcome variables analyzed were in-hospital mortality (IHM), length of hospital stay (LOS), and costs.Results: The total number of persons hospitalized with pH1N1 was 11,499. Of those, 9.44% suffered COPD. The most common underlying medical conditions among COPD patients included diabetes (18.60%) and obesity (9.94%). COPD was associated to a significantly higher IHM (3.04% vs. 2.40%, p<0.05), LOS (7.45 vs. 6.75, p<0.05) and cost per patient (4,040 vs. 2,991 €, p<0.05) that among non-sufferers. The results of the multivariate analysis showed that suffering COPD increased the risk of IHM in subjects admitted in Spanish hospitals due to pH1N1 in 2009 (OR=3.43; 95% CI 1.96-6.01). For COPD sufferers, those that died during the hospitalization with influenza pH1N1 were significantly older, suffered more concomitant chronic diseases and had a longer LOS and higher costs.Conclusions: Among individuals hospitalized in 2009 with pH1N1 infection in Spain the prevalence of COPD was 9.44%. The most common underlying medical conditions among COPD patients included diabetes and obesity. Suffering COPD increased the risk of IHM in subjects admitted to Spanish hospitals due to pH1N1 in 2009, after adjusting for other covariates.