RT Journal Article SR Electronic T1 Thoracoabdominal dyssynchrony and it relationship with muscle strength in patients with COPD: Preliminary results JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4152 VO 40 IS Suppl 56 A1 Renata Basso A1 Camila Pantoni A1 Eloisa Regueiro A1 Audrey Borghi-Silva A1 Mauricio Jamami A1 Valéria Pires Di Lorenzo A1 Dirceu Costa YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P4152.abstract AB Background: Upper limbs (UL) exercises can generate thoracoabdominal dyssynchrony (TD), which increase the dyspnea in patients with COPD. However, it is unknown the influence of posture and inspiratory muscle strength (IMS) in TD.Aim: To verify the TD in rest and UL exercises comparing sitting and standing posture and IMS.Methods: Fifteen patients with COPD (FEV1 47±16%pred, age 66±9, MIP 58±21cmH2O) performed flexion-extension exercises at the shoulder (1), above the shoulder (2) and horizontal abduction-adduction (3) in sitting and standing postures. The respiratory inductive plethysmography was performed (LifeShirt) and the Borg scale was reported. The PhRIB (Phase Relation during Inspiration), PhREB (during Expiration), PhRTB (Entire Breath) and PhAng (Phase Angle) were analysed (repeated measures test). In addition, patients were divided in two groups (MIP above and below 60%pred) (one-way ANOVA).Results: The TD increased during exercises. There was a significant increase of the variables (p<0.05) during exercise situation compared to rest in both studied postures, without differences between them. The group with MIP below 60%pred showed higher dyssynchrony in exercise 1 in sitting, and exercise 3 in standing. There was no difference in dyspnea in both groups. Table 1 summarizes the results.View this table:Conclusion: These preliminary results suggest that upper limb exercises cause TD independent of the postures adopted. In additional, the results suggest that the inspiratory muscle weakness seems get worse the dyssynchrony.RB is a fellow of CAPES.