PT  - JOURNAL ARTICLE
AU  - Aissa Ouardi
AU  - Mourad Hadjadj
AU  - Yahia Berrabah
TI  - Multidrug-resistant tuberculosis in the western region of Algeria
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P2686
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P2686.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P2686.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - INTRODUCTION:The MDR-TB is entirely man-made and is the result of a failure in effective implementation of anti-tuberculosis national plan (PNLT).What assessment do we have of curing it in the western region of Algeria?MATERIAL AND METHOD:A longitudinal descriptive study involving 97 patients followed for MDR-TB from January 2005 to December 2009 and put in 2nd line regimen with a duration of at least 21 months and including 05 drugs (Ofloxacin, Ethionamide, Kanamycin, Cycloserine and Pyrazinamide)Inclusion Criteria:Patient with MDR-TB documented to INH and Rifampicin at least.Patient who underwent at least 02 chemotherapy regimens including one eight-month regimen that always have positive smears.RESULTS:Average age: 29 yearsExtreme age: 15 to 61 years45% of patients aged between 25 and 34 years. Sex ratio 1,4.33% of patients from the wilaya of Mostaganem07 familial cases observed06 patients are diabetic, one patient with HIV co-infection.96% of exclusive lung locations92% of patients received at least 02 treatments before drug susceptibility testOf the 97 patients, 59 are cured, 14 patients in failure, 15 died and 09 have given up treatment.82,5% of patients have benefited from a drug susceptibility test, the resistance to INH and Rif is observed in 100% of cases, streptomycin in 50% of cases and Ethambutol in 23% of cases.For patients who have finished their treatment, the cure rate is 61%.CONCLUSION:MDR-TB represents a threat which we must face with determination, respecting and reviving the PNLT in order to prevent the emergence of multi- resistant bacilli.