RT Journal Article
SR Electronic
T1 Factors associated with the requirement of ventilatory support during an acute exacerbation of COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2010
VO 40
IS Suppl 56
A1 Rosalind Benson
A1 Anne Pocock
A1 Nosheen Kazmi
A1 Syed Huq
A1 Sanjeev Agarwal
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P2010.abstract
AB BackgroundInvasive or non-invasive ventilatory support is often required for patients hospitalised with acute exacerbation of COPD (AECOPD). We aimed to identify some baseline characteristics associated with subsequent requirement for ventilatory support.MethodsA retrospective study of consecutive patients admitted with AECOPD in an acute teaching hospital.Results67 patients (45% male) with a mean (SD) age of 72 (12), % predicted FEV1 of 55 (20) and baseline ECOG performance status (PS) of 2 (1.2) were studied. 10 (15%) required invasive or non-invasive ventilatory support at some point during their admission.View this table:Patient characteristics and admission parametersConclusionsPatients with AECOPD who subsequently required ventilatory support had a significantly lower SpO2, higher PaCO2 and a higher respiratory rate on admission. They also had a relatively better PS. Admission glucose and lactate levels were also important factors. Identifying high-risk patients based on these specific criteria on admission may help in managing patients with AECOPD more aggressively, thereby improving clinical outcomes.