TY - JOUR T1 - Physical activity in daily life in COPD after exercise training: Are there responders, and who are they? JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - 2836 AU - Nidia A. Hernandes AU - Thaís Sant'Anna AU - Carlos A. Camillo AU - Vanessa S. Probst AU - Fabio Pitta Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/2836.abstract N2 - Background: Previous studies have shown that patients with chronic obstructive pulmonary disease (COPD) generally do not increase their level of physical activity in daily life (PADL) after short-lasting exercise programs. However, as PADL is influenced by several factors, there are individual patients who respond positively becoming more active in daily life. Aims: To study the proportion and profile of patients with COPD who become more active in daily life after a 12-week exercise training program (responders). Methods: 23 patients (15 men, 66±8yrs, FEV142±16%pred) completed an exercise training protocol (endurance and strength exercises, 3x/week, 12 weeks). PADL was assessed by an activity monitor (Sensewear®, BodyMedia) which registered the time spent in physical activities of at least moderate intensity (TPA>mod). Other assessments were socio-economic and functional status, quality of life, exercise capacity, respiratory and peripheral muscle force. Responders were those who increased TPA>mod after the protocol. Results: 12 patients (52%) were responders (TPA>mod 10[3-28]min/day pre vs. 32[10-38]min/day post; p=0.002; median[IQR]). The proportion of physically active patients (i.e. TPA>mod ≥30min/day) increased after the protocol (26% vs. 39%, p=0.01). Although responders and nonresponders had similar physical and functional capacity, responders tended to present exertional desaturation (p=0.076), lower age (p=0.055) and live alone (p=0.089). Conclusions: These preliminary findings suggest that around half of patients with COPD increase their level of PADL after a 12-week exercise training program. Responders tend to be younger, live alone and desaturate during exertion. ER -