RT Journal Article SR Electronic T1 Presence of hypertension (HT), ischemic heart diseases (IHD) and a family history of hypertension are independently associated with reduced peak expiratory flow (PEF) values JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P4010 VO 40 IS Suppl 56 A1 Komalkirti Apte A1 Monica Barne A1 Bill Brashier A1 Sapna Madas A1 Jaideep Gogtay A1 Sushmeeta Chhowala A1 Basant Pachisia A1 Sundeep Salvi YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P4010.abstract AB Background: Reduced lung function has been shown to be an independent predictor of cardiovascular mortality in patients of hypertension and IHD in earlier studies.We aimed to study the association between HT, IHD and PEF values amongst road transport workers from Andhra Pradesh State in India.Methods: 7,154 bus drivers, conductors, garage workers and office-based workers of the Andhra Pradesh State Road Transport Corporation (APSRTC) were randomly selected from 24 bus depots and administered a health questionnaire, underwent blood pressure monitoring and performed peak flow metry using the EU scale peak flow meter (Breathometer®, Cipla Ltd., India). Current, past and family histories of cardiovascular and respiratory ailments were captured. Associations between PEF values and HT and IHD were studied using the chi square test and the values expressed as odds ratios.Results: Presence of HT, IHD and a family history of HT were independently associated with low PEF values, defined as less than 80% predicted PEFR value [OR 1.3, 95% CI 1.1 – 1.5, p=0.008; OR 1.9, 95% CI 1.2 – 3.0, p=0.004; OR 1.2, 95% CI 1.0 – 1.4, p=0.039 respectively]. No difference in odds ratios were observed between different occupations.Conclusion: PEF values less than 80% predicted are strongly associated with presence of HT, family history of HT and presence of IHD. Reduced peak flow values should stimulate the need for performing a cardiovascular assessment.