%0 Journal Article %A Selina Dürr %A Stefanie Zogg %A Sabrina Maier %A Esther Helen Steveling %A David Miedinger %A Jörg Daniel Leuppi %T Relationship between six-minute walk distance and chronic obstructive pulmonary disease assessment test %D 2012 %J European Respiratory Journal %P P3800 %V 40 %N Suppl 56 %X Background: Many patients with chronic obstructive pulmonary disease (COPD) are affected by the impairment in the ability to perform daily physical activities due to exercise intolerance, which can lead to a poor health-related quality of life.Aims and objectives: Our aim was to investigate the association of the six-minute walk distance (6MWD) and the COPD assessment test (CAT). We hypothesized that physical capacity has a more relevant association with quality of life than lung function.Methods: This cross-sectional study was conducted in 2011 at the University Hospital of Basel, Switzerland. Patients with COPD stages I to IV were investigated. Functional exercise capacity was measured by the six-minute walk test according to the guidelines of the American Thoracic Society. Spirometry was performed according to current guidelines. Health status was assessed by the CAT. A forced entry multiple regression analysis was calculated. The regression included 6MWD, forced expiratory volume in one second in % of predicted (FEV1%predicted), age and Body-Mass-Index (BMI). The dependent variable was the CAT-score.Results: Complete data were available for 73 individuals (age 67.0 ±9.8yrs, 58.9% male, FEV1%predicted 69.7 ±23.7%, 6MWD 434.5 ±99.1m, CAT-score 12.5 ±6.8, BMI 25.7 ±5.5). Age and 6MWD significantly contributed to the model (β= -0.49 respectively β= -0.46, p<0.01). BMI and FEV1%predicted did not significantly influence the CAT-score (β= -0.14 respectively β= -0.13).Conclusion: The association of the 6MWD and the CAT-score indicates that higher physical fitness level is related to improved health status and thus decreased impact of COPD on an individual's life. %U https://erj.ersjournals.com/content/erj/40/Suppl_56/P3800.full.pdf