RT Journal Article
SR Electronic
T1 Retrospective survival of COPD patients according to disease stage and pulmonary rehabilitation program
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3541
VO 40
IS Suppl 56
A1 Audhild Hjalmarsen
A1 Tormod Brenn
A1 Marijke Jongsma Risberg
A1 Kathrine Meisler Antonsen
A1 Elisabeth Kristiansen Benum
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P3541.abstract
AB The aim of this study was to examine the retrospective survival of patients with chronic obstructive pulmonary disease (COPD) according to type of pulmonary rehabilitation (PR) program and Global Initiative for Obstructive Lung Disease (GOLD) stage.Retrospectively, 193 patients (m / f 92 / 101, mean age 69.2 ± 8.6 SD) receiving PR were studied with lifetable analyses. FEV1 % pred. was significantly different in the in-patient (n = 72), out-patient (n = 72), and maintenance group (n = 49) [mean 54.5 ± 21.8 SD, 52.2 ± 17.7, and 42.9 ± 15.0, respectively (p &lt; 0.004)]. The impact of evaluated variables on survival in the three groups was significant for age, FEV1 and the use of long-term oxygen therapy (LTOT) (p &lt; 0.0001, HR 1.06, p &lt; 0.01, HR 0.98, and p &lt; 0.005, HR 2.18, respectively). Mean survival was eight years in GOLD stage 4 (n = 22), six in stage 3 (n = 79), and &gt;10 in stage 1 (n = 18) and 2 (n = 74). The impact of the evaluated variables on survival in the GOLD stages was significant for age, LTOT and stage 3 (p &lt; 0.0005, HR 1.05, p &lt; 0.001, HR 2.33, and p &lt; 0.02, HR 4.24, respectively). For the in-patient, out-patient and maintenance group days of PR were mean 30.3 ± 20.4 SD, 18.9 ± 10.4 and 30.0 ± 20.3, respectively (p &lt; 0.000), stays in hospital 0.35 ± 0.85, 0.86 ± 1.46, and 1.17 ± 1.60, respectively (p &lt; 0.003), and days in hospital 2.90 ± 8.89, 4.78 ± 8.26, and 9.04 ± 15.69, respectively (p &lt; 0.010).In conclusion, patients with GOLD stage 4 lived significantly longer than stage 3. Older age, decreased pulmonary function and LTOT predicted poorer survival in all PR groups. In addition to older age and LTOT, stage 3 predicted significantly poorer survival.