PT  - JOURNAL ARTICLE
AU  - Ahmed Sh. Mohamed
AU  - Ibrahim Ibrahim
TI  - Elective early noninvasive ventilation as a weaning method of COPD patients
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P2041
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P2041.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P2041.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Patients with acute exacerbations of COPD represent a large portion of critically ill patients that mechanically ventilated. The rate of weaning failure is high in these patients. Prolonged mechanical ventilation (MV) increases intubation associated complications. Objective: To determine the efficacy of early non-invasive mechanical ventilation as a weaning method in COPD patients with acute hypercapnic respiratory failure compared with the conventional-weaning approach. Methods: Study was conducted on a 30 mechanically ventilated COPD patients who had infective exacerbations. Patients were randomly extubated, receiving non-invasive ventilation (n=15), or weaned following a conventional-weaning approach (n=15). Results: compared with the convential-weaning group, the noninvasive-ventilation group had shorter periods of invasive MV, total ventilator support, ICU stay, less incidence of ventilator associated pneumonia and less mortality. Conclusion: Patients with chronic obstructive pulmonary disease who had respiratory failure and were starting to breathe spontaneously, showed that noninvasive ventilation could decrease pneumonia, length of stay in the intensive care and the duration of ventilatory support.View this table:Outcome parameters in both studied groupsRef. Manthous CA. The anarchy of weaning techniques. Chest 2002;121:1738-40.