RT Journal Article
SR Electronic
T1 Assessment of the prevalence of obstructive sleep apnea in patients with undiagnosed chronic cough
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P1877
VO 40
IS Suppl 56
A1 Mohamed Zidan
A1 Hany Shaarawy
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P1877.abstract
AB Background: Recent reports have suggested an association between chronic cough and obstructive sleep apnea (OSA). There is also evidence that treatment of sleep apnea can improve chronic cough. Objective: Is to assess the prevalence of OSA in patients with undiagnosed chronic cough and the effect of using CPAP therapy on the improvement of cough in those patients. Methods: The present study included 100 non smoker patients complaining of cough for more than 8 weeks without obvious diagnosis, after exclusion of any parenchymal lung or mediastinal diseases using chest X-ray, CT chest, pulmonary function testing, and methacholine challenge test to exclude cough variant asthma, patients undergone full polysomnography to screen for OSA and in whom proved to have the diagnosis, CPAP was tried for 2 weeks then follow up of the cough frequency and severity was done. Results: The study included 100 patients, with 60% females and 40% males, the duration of cough in weeks was 18.16±6.01 weeks, the most common cause of cough was gastroesophageal reflux disease (GERD) which was present in 70% of cases followed by upper airway cough syndrome (UACS) which was present in 50% of cases, OSA was present in 25% of patients in association with GERD in 15 patients and in association with UACS in 10 patients (10%). There was significant improvement of cough after using CPAP for 2 weeks (visual analogue scale (VAS) dropped from 82.4±8.6 mm to 7.4±5.11 mm after use of CPAP). Conclusion: OSA should be ruled out in patients with undiagnosed chronic cough as it is a common finding. CPAP seems to be an effective tool in treating those patients.