PT - JOURNAL ARTICLE AU - Alexandru Corlateanu AU - Victoria Slutu AU - Victor Botnaru AU - Doina Rusu TI - Evaluation of the quality of life with COPD assessment test DP - 2012 Sep 01 TA - European Respiratory Journal PG - P3452 VI - 40 IP - Suppl 56 4099 - http://erj.ersjournals.com/content/40/Suppl_56/P3452.short 4100 - http://erj.ersjournals.com/content/40/Suppl_56/P3452.full SO - Eur Respir J2012 Sep 01; 40 AB - Background:COPD Assessment Test (CAT) is a short, simple questionnaire for assessing and monitoring chronic obstructive pulmonary disease (COPD) patients. It was demonstrated that it has good measurement properties, is sensitive to differences in state and should provide a valid, reliable and standardised measure of COPD health status.The aim of this study was to investigate the factors that can predict HRQL in patients with COPD.Methods:60 consecutive COPD patients were enrolled into the study. We analyzed age, gender, anthropometric, pack years, spirometric data (FEV1, FVC, FEV1/FVC), BODE index (BMI, FEV1, MRC, 6 MWD). Health-related quality of life was assessed by the CAT and the St. George Respiratory Questionnaire (SGRQ).Results:60 COPD patients were studied, mean age was 60.2±7.5 years, mean FEV1, % was 34.6±11.3%. Patients across all stages GOLD/ATS/ERS classification had similar age and pack/years (p>0.01). Pearson correlation coefficient analysis demonstrates in COPD patients a significant positive correlation between the CAT and the total score of the SGRQ (r=0.59, p<0.01). Also correlations between CAT and MRC score are significant (r=0.48, p<0.01). CAT score correlated negatively with 6 MWD (r = -0.52, p<0.01). The forward stepwise regression analysis shows that the age, dyspnoea and oxygen saturation are important predictors of HRQL in COPD patients which explains 58% of the CAT score.Conclusion:COPD Assessment Test is a useful instrument to assess disease impact in COPD. Age, dyspnoea and oxygen saturation in patients with COPD are independent risk factors for worsening of HRQL.