RT Journal Article
SR Electronic
T1 The change of complication rate in chemical pleurodesis after replacement of talc preparation from small to large particle size-A longitudinal cohort study
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3359
VO 40
IS Suppl 56
A1 Hoi Nam Tse
A1 Ka Yan Wai
A1 King Ying Wong
A1 Kwok Sang Yee
A1 Lai Yun Ng
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P3359.abstract
AB Background: Talc particle size is an important determining factor for complication in talc pleurodesis.Aims: To investigate any change in complication rate for talc pleurodesis after replacement of talc preparation from small to large particle sizeMethods: It is a longitudinal cohort study conducted in Kwong Wah Hospital, Hong Kong. Talc preparation was changed from small (mean diameter<10µm) to large particle size (Steritalc©:mean size:31.3µm) since 1st Jan,10. Patients who received new talc prepartion(1st Jan 10 to 31st Dec,11) were compared to those received old talc preparation(1st Jan07 to 31st Dec09). The safety profile and efficacy of pleurodesis were compared between the 2 groups.Results: 141 patients were recruited. Since the change of talc prepration from small to large particle size, ARDS was totally eliminated. Post-pleurodesis fever was significantly reduced from 30.7 to 9.4%, resulting in a significant drop in antibiotic use.View this table:Complications rate in chemical pleurodesis since the change of talc preparation from small to large particle sizeMoreover, the efficacy of chemical pleurodesis was not jeopardized.Conclusions: There was a significant reduction in complication rates in chemical pleurodesis after replacement of the talc preparation from small to large particle size.