PT  - JOURNAL ARTICLE
AU  - Janos Varga
AU  - Bettina Pogany
AU  - Eva Mathene Koteles
AU  - Attila Somfay
TI  - Exercise induced reduction in dynamic hyperinflation after interval training with oxygen breathing
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - P1901
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/P1901.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/P1901.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Bakground: Exercise training reduces exercise induce dynamic hyperinflation (DH) at submaximal exercise (80% of peak work rate) in patients with COPD. Oxygen has dose-dependent effect (maximal at FiO2:0.3) on operating lung volumes in COPD.Methods: 10 COPD patients with moderate obstruction (FEV1: 53±12%pred, age: 63±10 yrs, BMI: 26±4 kg/m2) performed an incremental exercise test to maximal exercise tolerance, and two constant work rate test (CWR, 80% of peak work rate) with inspiratory capacity (IC maneuver for DH) in every 2 minutes before and after training. Patients performed interval training (1 minute 40% and 1 minute 80% of peak work rate) 3 times a week for 8 weeks breathing oxygen (5 patients 3L/min., group O) or compressed air (5 patients 3 L/min., group C) during training.Results: The initial peak work rate did not differ significantly between the groups (O: 94±18 vs. C: 86±19 W). Endurance improved in both group (O: 425±110 vs. 630±122, C:370±120 vs. 555±126 sec, p<0.05), oxygen uptake increased in group O (VO2 O:1.20±0.12 vs. 1.36±0.10 L/min., p<0.05) after training. In group O, there was a tendency to reduction in DH after training (IC 1: 2,33±0,62 vs. 2,44±0,90; 2: 2,25±0,73 vs. 2,37±0,94; 3: 2,36±0,96 vs. 2,55±0,97; 4: 2,24±1,00 vs. 2,36±1,01; 5: 2,24±1,00 vs. 2,36±1,01; 6: 2,23±0,97 vs. 2,33±1,00; 7: 2,36±0,73 vs. 2,00±1,02 L). IC did not change in group C.Conclusion: The pilot study revealed less hyperinflation tendency and improved oxygen uptake in group O, which might refer to better physiologic training effect.