TY - JOUR T1 - Misdiagnosed pulmonary TB: Influencing factors and diagnostic chances in TB hospital JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P2720 AU - Zhanna Laushkina AU - Pavel Filimonov Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P2720.abstract N2 - Differential diagnosis of pulmonary TB is still difficult. We found the tendency to overdiagnosis of pulmonary TB in TB hospital.Purpose of the study was to analyze causes of diagnostic errors and improve the quality of in-hospital management of patients supposed to having of pulmonary TB.Methods: Noncomparative retrospective study, subject of interest were medical records of 136 most difficult cases, in which previously established diagnosis of pulmonary TB was rejected. The chances for establishment of true diagnosis and influencing factors were estimated.Results: 1. Diseases, most often initially misdiagnosed as tuberculosis, were pneumonia (52 %), lung cancer (20 %). 2. The period from the disease manifestation up to establishment of final diagnosis was 84 ± 72.8 (mean±SD) days. 3. Clinicoradiological signs in these cases were more characteristic for TB, than for other pulmonary diseases. 4. Factors found to be associated with false-positive diagnosis is: “limited pulmonary opacity” (OR 1.75, p=0.003), pulmonary dissemination (OR 1.75, p=0.05), detection of low level acid-fast bacilli in sputum (OR 2.0, p=0.04), nonspecific inflammatory findings detected by flexible bronchoscopy (OR 2.2, p=0.000), age more than 40 years (OR 1.75, p=0.01), inconspicuous disease onset (OR 1.9, p=0.01), COPD (OR 1.8, p=0.04), inadequate antibacterial therapy before hospitalization.Conclusion: Application of contemporary methodologies of diagnostic tests interpretation, use of rapid TB diagnostic is highly needed. ER -