RT Journal Article SR Electronic T1 Study of thoracoscopic pleural biopsy for nondiagnostic pleural effusion JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1259 VO 40 IS Suppl 56 A1 YuJin Kim A1 Sun Young Kyung A1 Sang Pyo Lee A1 Sung Hwan Jeong A1 Shin Myung Kang A1 Sang Min Lee A1 Jeong-Woong Park YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P1259.abstract AB Background: We performed thoracentesis and pleural biopsy by cope needle to find cause of exudative pleural effusion. Usually about 20% of them can't find cause. We study thoracoscopic biopsy for nondianostic patients and charateristics of diseases.Method: We enrolled patients from April 2004 to May 2010. We included patients with nondiagnostic pleural effusion through sputum study, thoracentesis, washing microbiologic study and cytology by bronchoscopy. Twenty-six patients were performed thoracoscopic pleural biopsy.Result: Twenty-four patients were identified. Their mean age was 60.5±15.3years, and 16(66.7%) of the patients were men. Four patients weren't performed thoracentesis. Charateristics of pleural effusion were lymphodominent (15; 75%), poly-dominent(2;10%), eosinophil dominant (1;5%) and unknown(2;10%). Final diagnosis of patients with undiagnostic pleural effusion were malignant effusion (n=14, 58.3%), Tb pleuray(n=3, 12.5%), chronic inflammation and fibrosis(n=5, 20.8%) and hemorrhagic effusion and eosinophilic effusion (n=2, 8.3%). The most common cause of malignant effusion was secondary not primary lung cancer. Metastatic effusion were 5 patients (35.7%). Malignant mesothelioma were 3patients (21.4%). adenocarcinoma of unknown origin were 2patients (14.3%). Primary lung cancer were 4patients (25.8%).Conclusion: Fifteen patients(58.3%) of nondianostic effusion were diagnosed malignant effusion. In These 15 patients, secondary malignant effusion were 10.patients(74.3%). In Conclusion, we consider thoracoscopic biopsy and systemicexamination to identified nondianostic pleural effusion.