TY - JOUR T1 - Pulmonary rehabilitation in advanced lung cancer patients during chemotherapy - Preliminary report JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P1902 AU - Dariusz Jastrzebski AU - Grzegorz Hydzik AU - Malgorzata Maksymiak AU - Anna Poczatek AU - Sabina Kostorz AU - Dariusz Ziora AU - Jerzy Kozielski Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P1902.abstract N2 - Objectives: The aim of this study was to investigate the utility of a pulmonary rehabilitation (PR) program on mobility, pulmonary function, dyspnea and quality of life in patients with advanced lung cancer during chemotherapy.Methods: This study included patients with newly diagnosed advanced lung cancer. Study group consisted of 12 pts with advanced non-small cell lung cancer and 5 pts with small cell lung cancer. Pulmonary function (FVC, FEV1), mobility (6 MWT), perceived of dyspnea (MRC, OCD, BDI) and quality of life (SF-36, EORTC) was analyzed before and after the intervention. The inpatients rehabilitation program was based on Nordic Walking exercise training and respiratory muscle training. Sessions occurred twice daily, each lasting approximately 60 minutes with 10-minute warm-up period.Results: Intention-to-treat analysis indicated that 6MW distance increased 55m (95% CI, 18-75, p=.012) with no changes in pulmonary function tests (FVC, FEV1). Perceived of dyspnoea was improved in Oxygen Cost Diagram (2.4 vs. 1.3, p=.012), FI/BDI (1.7 vs. 2.4, p=.008) and overall score BDI (4.4 vs. 6.4, p=.006). General quality of life questionnaire showed improvement in Role-Physical, Bodily-Pain, Social-Functioning and Physical Cumulative Score of SF-36 without statistically significance. Lung cancer questionnaire showed significantly improvement (p<.05) in perception of dyspnoea, exercise tolerance, quality of life, improvement in social functioning, everyday living and decrease of consumption analgesic drugs.Conclusion: Pulmonary rehabilitation in advanced lung cancer patients during chemotherapy is a beneficial intervention to improvement in their lung cancer symptoms and mobility. ER -