PT  - JOURNAL ARTICLE
AU  - Gaelle Rousseau-Bussac
AU  - Dimitri Margetis
AU  - Anne Lino
AU  - Arnaud Galbois
AU  - Sophie Phin-Huynh
AU  - Eric Maury
AU  - Christos Chouaid
TI  - Prognosis of patients with a lung cancer admitted in intensive care unit
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - 3269
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/3269.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/3269.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Admission in ICU (Intensive Care Unit) of patients with lung cancer is still debated. The argument against admission is often their bad prognosis.We retrospectively included all consecutive patients with a lung cancer histologically proved admitted in ICU for more than 24 hours between January 2003 and December 2010.104 patients were included with a median SAPS 2 of 54.5; 52% of patients were metastatic. 55 (53%) patients needed invasive mechanical ventilation. Mortality rates in ICU, in hospital and at one year were respectively 31.7%, 48% and 83.7%. Prognostic factors were SAPS 2 score ≥ 42 (OR 2,65 IC 95% (1,10-6,36), p=0,03), invasive mechanical ventilation (OR 4,88 IC 95% (1,86- 12,76), p=0,012), vasopressive treatments (OR 6,26 IC95% (2,52- 15,57), p<0,001) and organ dysfunction with need of mechanical invasive ventilation or non-invasive ventilation or vasopressive treatments or dialysis (OR 5,5 IC95% (1,12- 27,2), p=0,0002) in univariate analysis. 75% of survivors of ICU will benefit of specific anticancer treatment after their hospitalisation in ICU. In a Kaplan-Meier survival curve, metastasis group and without metastasis group have a significant difference of median survival whatever the acute complication that conducted to ICU admission (p=0.019).Prognostic factors in ICU seems to be related to the acute pathology, otherwise long term prognosis is determined by cancer prognosis.