RT Journal Article
SR Electronic
T1 Computed tomography of the paranasal sinuses in chronic obstructive pulmonary disease
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P3962
VO 40
IS Suppl 56
A1 Esther Helen Steveling
A1 Caroline Newerla
A1 Selina Dürr
A1 Claudia Gerhards
A1 Sabrina Maier
A1 Christoph Stippich
A1 Antje Welge-Lüssen
A1 Stefanie Zogg
A1 David Miedinger
A1 Jörg Daniel Leuppi
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P3962.abstract
AB Background: Pathologic correlates of the upper airways have been rarely evaluated in chronic obstructive pulmonary disease (COPD).Aims: Assessment of objective and subjective impairment of the upper airways in COPDMethods: Computed tomography (CT) of the paranasal sinuses was performed in patients with COPD and evaluated using the Newman scoring system (>0 points considered abnormal). Nasal endoscopy was performed and scored according to Lund and Kennedy (>1 point considered abnormal). Rhinosinusitis related quality of life and symptoms were assessed with the Sino Nasal Outcome Test-20 (SNOT-20) (>12 points considered abnormal) and the SNOT-primary nasal symptoms score (SNOT-PNS). Spirometry was performed according to established guidelines. Patients were classified into COPD risk groups according to the GOLD guidelines of December 2011 considering symptoms, COPD stages 1-4 and exacerbations.Results: We included 83 patients (35 women) with a mean age of 68 years (range: 44-90). 29 subjects (35%) were in COPD risk group A, 38 subjects (46%) in risk group B and 16 subjects (19%) in risk groups C and D. Abnormal CT scores were observable in 49 subjects (59%) and abnormal endoscopies were found in 51 subjects (61%). 51 subjects (61%) scored abnormal results in the SNOT-20. We found a positive correlation between the CT score and the SNOT-PNS (r=.22, p<.05). The endoscopic score correlated positively with the SNOT-PNS (r=.29, p<.05) as well as with the SNOT-20 (r=.42, p<.01). Subjects in higher risk groups presented higher scores in endoscopy (p<.05), SNOT-PNS (p<.05) and SNOT-20 (p<.01).Conclusion: Pathologic correlates of the upper airways were found in more than half of the patients with COPD.