PT - JOURNAL ARTICLE AU - Yu Chen AU - Shiyue Li TI - A pilot study for benign central airway stenosis: Local injection of triamcinolone acetonide therapy DP - 2012 Sep 01 TA - European Respiratory Journal PG - P3351 VI - 40 IP - Suppl 56 4099 - http://erj.ersjournals.com/content/40/Suppl_56/P3351.short 4100 - http://erj.ersjournals.com/content/40/Suppl_56/P3351.full SO - Eur Respir J2012 Sep 01; 40 AB - Objectives:To evaluate the efficacy and security of local injection of Triamcinolone acetonide(TA) for benign central airway stenosis(BAS).Methods: Forty intractable BAS patients were selected and averagely divided into treatment group and control group. Local injection of TA was uesd to cover entire stenosis lesions. Interventional procedures were combined to manage complicated airway stenosis. After a 6 months follow-up, compared two groups with airway diameter, stricture rate, dyspnea score, and clinical stabilizationbefore and after the treatment.Results:No statistically significant differences in the two groups. A 6 months follow-up, 16 patients remain stable after treatment, besides 4 patients appear restenosis in treatment group, compare with Control group 20 cases restenosis. Restenosis interphase time and clinical stabilization time was markedly increased.View this table:TA group treatment resultsView this table:TA group compare with control group after 6 months follow upNo local injections related complications was recodred.Conclusion:Local injections of TA therapy combined with traditional interventional techniques for BAS has good curative effect. It shows advantages in long-term efficacy, few side-effects, and good safety.