TY - JOUR T1 - Evaluation of characteristics and treatment results of patients treated as multidrug resistant tuberculosis JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P3326 AU - Murat Yalçinsoy AU - Hüseyin Arpag AU - Tülin Kuyucu AU - Ates Baran AU - Mualla Partal AU - O. Kaya Köksalan AU - Esen Akkaya Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P3326.abstract N2 - Multi-drug resistant tuberculosis (MDR-TB) is a disease that's treatment is more difficult, more therapeutic efficacy and toxicity of drugs used than drug-sensitive TB. Cure rates are very different in the treatment of MDR-TB. In this study, features and treatment outcomes of MDR-TB patients followed in two clinics of our hospital were reported.Among 79 MDR-TB patients, 58 (%73.4) were male, 21 (%26.6) were female; the mean age was 36.24±13.75 (17-70) and all were HIV(-). 64 patient's treatment were completed and 15 patients are still under treatment. In 27 cases (34.2%) had tuberculosis contact and 7 cases (9%) had a family history of MDR-TB. 25 (31.6%) cases had comorbid disease. 35 patients (44.3%) were evaluated as primary and 44 (55.7%) were evaluated as secondary MDR-TB. The average day of hospitalization was 162.76 (30-436). Radiologically, 11 (14%) cases had common, 68 (86%) patients had limited disease. A mean number of 5.18±0.5 (5-7) second line drugs were administered, adverse effects of drugs were identified in 36 (%45.5) patients. Sputum and culture conversion were provided at mean 1.8 ± 1.3and 1.9 ± 1.03 months in patients completed treatment, respectively. Of the patients completed treatment, %84.4 (n=54) were classified as cured, %7.8 (n=5) were defaulters and %7.8 (n=5) died during treatment. Surgical resection was applied in 2 patients. Treatment of 14 patients is still going on and sputum conversions were provided mean 1.6. months.Conclusion, At the end of the study, very high cure rate found in MDR-TB cases young and had limited disease radiologically. ER -