RT Journal Article
SR Electronic
T1 Non invasive proportional assist ventilation in management of severe asthma exacerbation
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP P2023
VO 40
IS Suppl 56
A1 Khaled Hussein
A1 Mohamed Metwally
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/P2023.abstract
AB Background: NIV could be beneficial in selected patients with severe asthma exacerbation (SAE). However, its role is still not well defined.Objective: To evaluate the efficacy of NIV using proportional assist ventilation (PAV) in SAE after failure of conventional medical treatment (CMT).Patients&Methods:Thirty patients with SAE were failed to respond on CMT. NIV was applied via face mask as a last resort before intubation.Results:The mean age was 39.2 ± 9.7 with female predominance (19 females Vs 11 males). The successful outcome was achieved in 23/30 patients (76.6%). Follow up of respiratory distress and gasometric parameters after 1 hour NIV in successful group was shown in table 1.View this table:Table1: Follow up of respiratory distress and gasometric parameters after 1h NIVPEFR in successful and failure groups are shown in figure 1.After 1h NIV, there were significantly (P<0.01) higher tidal volume, peak inspiratory pressure and triggered breaths % in successful group Vs failure group.Conclusion:NIV can relieve respiratory distress and improve gas exchange in majority of patients with severe asthma exacerbation who are candidate for intubation after failure of CMT.