RT Journal Article SR Electronic T1 Effect of interval training on the BODE index, SF-36, EuroQol and St-George's Respiratory Questionnaires scores in COPD patients across GOLD stages I-IV JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1897 VO 40 IS Suppl 56 A1 Vasileios Andrianopoulos A1 Stavroula Spetsioti A1 Alexandra Chatzi A1 Nikolaos Chinkiamis A1 Ioannis Nasis A1 Theodora Vasilogiannakopoulou A1 Anastasia Panagopoulou A1 Emmanouela Kostaki A1 Georgia Koutsoflini A1 Nikolaos Koulouris A1 Ioannis Vogiatzis YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P1897.abstract AB In COPD patients, functional capacity, health-related quality of life and health status are respectively assessed by the clinical tools of BODE index, SF-36, EuroQol and St-George's Respiratory Questionnaires. Interval training as a therapeutic modality elicits substantial physiological effects; however, the impact of interval training to those tools across the whole spectrum of COPD severity still remains unknown. Objective: To investigate whether beneficial effect of interval training is reflected to BODE and the 3 Questionnaires in GOLD stages(I-IV). Methods: In a large cohort of 106 COPD patients, rehabilitative intervention and control groups consisted of 71 and 35 patients, respectively. Exercise training involved 30min cycling by alternating 30-s exercise intervals at 100%Wpeak with 30-s rest and large-muscle group resistance training for a period of 10 weeks, 3-times/week. Results: Interval training improved significantly the clinical condition of patients across GOLD stages:II.(BODE:1.9 vs 1.1, SF-36pcs:39.6 vs 44.9, SF-36mcs:43.7 vs 49.3, EuroQol-VAS:54.1 vs 70.8, St-George's:50.5 vs 38.9), III.(BODE:3.8 vs 2.3, SF-36psc:38.5 vs 43.0, SF-36mcs:40.1 vs 47.4, EuroQol-VAS:48.6 vs 65.5, St-George's:52.6 vs 40.4), IV.(BODE:5.7 vs 4.1, SF-36psc:33.1 vs 40.9, SF-36mcs:33.2 vs 46.3, EuroQol-VAS:40.4 vs 58.2, St-George's:60.1 vs 46.2) (P<0.05). Non significant changes were shown for patients in GOLD stage I and the control group. Conclusions: Beneficial effects of interval training in functional capacity, health-related quality of life and physical status are reflected by improved clinical condition of patients in GOLD stages II-IV.