PT - JOURNAL ARTICLE AU - Vasileios Andrianopoulos AU - Stavroula Spetsioti AU - Alexandra Chatzi AU - Nikolaos Chinkiamis AU - Ioannis Nasis AU - Theodora Vasilogiannakopoulou AU - Anastasia Panagopoulou AU - Emmanouela Kostaki AU - Georgia Koutsoflini AU - Nikolaos Koulouris AU - Ioannis Vogiatzis TI - Effect of interval training on the BODE index, SF-36, EuroQol and St-George's Respiratory Questionnaires scores in COPD patients across GOLD stages I-IV DP - 2012 Sep 01 TA - European Respiratory Journal PG - P1897 VI - 40 IP - Suppl 56 4099 - http://erj.ersjournals.com/content/40/Suppl_56/P1897.short 4100 - http://erj.ersjournals.com/content/40/Suppl_56/P1897.full SO - Eur Respir J2012 Sep 01; 40 AB - In COPD patients, functional capacity, health-related quality of life and health status are respectively assessed by the clinical tools of BODE index, SF-36, EuroQol and St-George's Respiratory Questionnaires. Interval training as a therapeutic modality elicits substantial physiological effects; however, the impact of interval training to those tools across the whole spectrum of COPD severity still remains unknown. Objective: To investigate whether beneficial effect of interval training is reflected to BODE and the 3 Questionnaires in GOLD stages(I-IV). Methods: In a large cohort of 106 COPD patients, rehabilitative intervention and control groups consisted of 71 and 35 patients, respectively. Exercise training involved 30min cycling by alternating 30-s exercise intervals at 100%Wpeak with 30-s rest and large-muscle group resistance training for a period of 10 weeks, 3-times/week. Results: Interval training improved significantly the clinical condition of patients across GOLD stages:II.(BODE:1.9 vs 1.1, SF-36pcs:39.6 vs 44.9, SF-36mcs:43.7 vs 49.3, EuroQol-VAS:54.1 vs 70.8, St-George's:50.5 vs 38.9), III.(BODE:3.8 vs 2.3, SF-36psc:38.5 vs 43.0, SF-36mcs:40.1 vs 47.4, EuroQol-VAS:48.6 vs 65.5, St-George's:52.6 vs 40.4), IV.(BODE:5.7 vs 4.1, SF-36psc:33.1 vs 40.9, SF-36mcs:33.2 vs 46.3, EuroQol-VAS:40.4 vs 58.2, St-George's:60.1 vs 46.2) (P<0.05). Non significant changes were shown for patients in GOLD stage I and the control group. Conclusions: Beneficial effects of interval training in functional capacity, health-related quality of life and physical status are reflected by improved clinical condition of patients in GOLD stages II-IV.