PT - JOURNAL ARTICLE AU - Vladimir Stanoev AU - Georgi Yankov AU - Michail Plochev AU - Eluar Goranov AU - Rosen Petkov AU - Danail Petrov TI - Lung metastases from colorectal cancer - Surgery, early and late postoperative results DP - 2012 Sep 01 TA - European Respiratory Journal PG - P1252 VI - 40 IP - Suppl 56 4099 - http://erj.ersjournals.com/content/40/Suppl_56/P1252.short 4100 - http://erj.ersjournals.com/content/40/Suppl_56/P1252.full SO - Eur Respir J2012 Sep 01; 40 AB - Aim: To make a retrospective study of results after surgical treatment of pulmonary metastases from colorectal cancer.Methods: A total of 52 patients with pulmonary metastases from colorectal cancer were operated. Unilateral operations were performed in 40 (76.9%) patients. Bilateral operations were carries out in 12 (23.1%) patients. In 9 (17.3%) of them one stage operation was performed and in 3 (5.8%) - two stages operations were performed. The approach in 6 (11.5%) of one-stage operations was sternotomy and in 3 (5.8%) were bilateral thoracotomy. Unilateral operations were performed in 33 (63.4%) cases by thoracotomies and 7 (13.5%) by VATS. Precise metastasectomy was made in all patients with bilateral metastases. In unilateral metastases were performed 27 (51.9%) metastasectomies, 8 (15.4%) lobectomies, 2 (3.8%) extended lobectomies, 2 (3.8%), sleeve lobectomies and 1 (1.9%) polysegmentectomy.Results: No 30-day postoperative mortality was observed. In 3 (5.8%) cases there were minor complications. The overall five-year survival was 25%. Only resectability of metastases (p<0.001), duration of disease-free interval (p=0.002) and the presence of unilateral or bilateral lesions (p=0.001) were proved to be significant prognostic factors. Unfavourable prognostic factors, but without statistical significance were the number of metastases and the involvement of mediastinal lymph collectors.Conclusions: Surgical resection is a standard approach for isolated lung metastases from collorectal carcinoma. Resectability of metastases, duration of disease-free interval and the presence of unilateral or bilateral lesions are significant prognostic factors.