RT Journal Article
SR Electronic
T1 Correlation between gas-exchange dynamics in recovery of exercise tests and cardiovascular parameters in pulmonary hypertension
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP 4333
VO 40
IS Suppl 56
A1 Patrick Jak
A1 Harm-Jan Boogaard
A1 Anton Vonk-Noordegraaf
YR 2012
UL http://erj.ersjournals.com/content/40/Suppl_56/4333.abstract
AB Introduction: In pulmonary hypertension (PH), cardiac dysfunction and gas exchange abnormalities within the lung may both delay the rate of recovery in O2-uptake (V'O2) and CO2-release (V'CO2) after a cardiopulmonary exercise test (CPET).Aim: Determine the correlation between recovery rates of V'O2,V'CO2 after CPET with pulmonary vascular resistance (PVR) and right ventricular ejection fraction (RVEF).Method: In this retrospective study measurements on 12 PH-patients were used. 1-4 CPETs and heart catheterisations (for PVR measurement) per patient were done. Sometimes also a cardiac MRI was performed, rendering RVEF.View this table:test group characteristicsResults: Changes in V'O2,V'CO2 strongly correlated with PVR and RVEF.Conclusion: In PH-patients, slow recovery-rates of VO2 and VCO2 are associated with a high PVR and low RVEF.