PT  - JOURNAL ARTICLE
AU  - Patrick Jak
AU  - Harm-Jan Boogaard
AU  - Anton Vonk-Noordegraaf
TI  - Correlation between gas-exchange dynamics in recovery of exercise tests and cardiovascular parameters in pulmonary hypertension
DP  - 2012 Sep 01
TA  - European Respiratory Journal
PG  - 4333
VI  - 40
IP  - Suppl 56
4099  - http://erj.ersjournals.com/content/40/Suppl_56/4333.short
4100  - http://erj.ersjournals.com/content/40/Suppl_56/4333.full
SO  - Eur Respir J2012 Sep 01; 40
AB  - Introduction: In pulmonary hypertension (PH), cardiac dysfunction and gas exchange abnormalities within the lung may both delay the rate of recovery in O2-uptake (V'O2) and CO2-release (V'CO2) after a cardiopulmonary exercise test (CPET).Aim: Determine the correlation between recovery rates of V'O2,V'CO2 after CPET with pulmonary vascular resistance (PVR) and right ventricular ejection fraction (RVEF).Method: In this retrospective study measurements on 12 PH-patients were used. 1-4 CPETs and heart catheterisations (for PVR measurement) per patient were done. Sometimes also a cardiac MRI was performed, rendering RVEF.View this table:test group characteristicsResults: Changes in V'O2,V'CO2 strongly correlated with PVR and RVEF.Conclusion: In PH-patients, slow recovery-rates of VO2 and VCO2 are associated with a high PVR and low RVEF.