RT Journal Article SR Electronic T1 The relation between prevalence of chronic respiratory symptoms and ventilatory dysfunctions - A crossectional study in a industrial area from Constanta Harbor JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P984 VO 40 IS Suppl 56 A1 Ghiulten Apti A1 Anamaria Trailescu A1 Hayat Memis A1 Cristian Didilescu YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P984.abstract AB Aims: to estimate the prevalence of chronic respiratory symptoms(CRS) and relation with ventilatory parameters in a environment with occupational exposure to inhalatory noxes;Material and method: epidemiologic crossectional study on 539 workers Constanta harbor,aged between17-65 years(mean 42,95) male 88,7%,without prior respiratory diseases;data were collected by CRSQ,self reported exposure, smoking habit, history of exposure,spirometry;Results: 87,4% exposed at least to one noxe; predominated exposure to dust 75,5%;exposure time more than 20 years in 59,2%; exposure high and very high in 42,8%; smokers 56,2%,exsmokers 13,7%;symptoms occurred in 55%:chronic cough in 45%(OR=2,3), phlegm in 40,6%(OR=1,03), dyspneea 22,8 % OR=1,5 (gr≥2 only 32,6%)-all predominated in exposed and smokers; wheezing 12,8%-predominated in nonsmokers; spirometric parameters were lower in symptomatic significant for exposed; cough, dyspneea grade≥ 2 and wheezing were associated with low averages of FEV1,FEF50(p<0,001); FEV1 means were lower in high exposed; 78,3% had normal spirometry;17,4% obstructive dysfunction(OD), 2,8% restrictive dysfunction(RD) ;OD was correlated with high exposure and >20 years exposure; ventilatory dysfunctions higher in symptomatics(OR=5,7 for high exposed); cough and dyspneea were strong associated(corr=0,46 ;p<0,0001) with distal OD(OR=3,9);Conclusions: the prevalence of CRS was high, related to exposure and smoking; chronic cough and dyspneea≥2 were more predictive for ventilatory dysfunctions; obstructive dysfunctions are predominant in occupational environment, in relation with level and time of exposure.