TY - JOUR T1 - Cardiorespiratory fitness, pulmonary function and C-reactive protein levels in adults with diabetes JF - European Respiratory Journal JO - Eur Respir J VL - 40 IS - Suppl 56 SP - P4145 AU - Cristina Oliveira Francisco AU - Aparecida Maria Catai AU - Silvia C.G. Moura AU - Sérgio L.B. Lopes AU - Adriano M. Del Vale AU - Angela M.O. Leal Y1 - 2012/09/01 UR - http://erj.ersjournals.com/content/40/Suppl_56/P4145.abstract N2 - Background/Aim: Diabetes Mellitus (DM) is associated with impairment of cardiorespiratory fitness and pulmonary function; increasing evidences have suggested that comorbidities and systemic inflammation may be involved. The objective of this study was evaluate changes in metabolic variables, C-reactive protein (CRP) levels, cardiorespiratory fitness and pulmonary function in DM patients compared with healthy subjects. Methods: 19 men with diabetes (49±2 years) and 19 healthy control subjects (51±1 years) were studied. All subjects performed a spirometry and an incremental cardiopulmonary exercise test on a cycloergometer with electromagnetic breaking (workload increases, range 13-22W/min). Cardiopulmonary data were continuously collected with a metabolic unit. Heart rate (HR) was continuously monitored. Results: are presented in table 1.View this table:Table 1. Lung function, physical capacity parameters and CRP levels.Conclusion: The cardiorespiratory fitness is reduced in patients with diabetes but the spirometric values are preserved, and the CRP did not differ of the control subjects.Financial support: Capes, FAPESP. ER -