RT Journal Article SR Electronic T1 Relationship between COPD assessment test (CAT) and declines of lung function in COPD patients JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P3451 VO 40 IS Suppl 56 A1 Hyun Jung Kwak A1 Ji-Yong Moon A1 Tae Hyung Kim A1 Sang-Heon Kim A1 Jang Won Sohn A1 Dong Ho Shin A1 Sung Soo Park A1 Ho Joo Yoon YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P3451.abstract AB Background: COPD assessment test (CAT) is a recently developed questionnaires used for assessing and monitoring chronic obstructive pulmonary disease (COPD). However, the relationship with CAT score and the other clinical parameters of COPD are not well determined yet. In this study, we aimed to investigate if CAT score is associated with the measures of clinical courses such as annual decline of lung function and acute exacerbation of COPD.Methods: We enrolled the patients with COPD, who were followed for more than two years. CAT and St. George Respiratory Questionnaire (SGRQ) were performed and information of clinical parameters of COPD was collected in a retrospective manner.Results: A total of 77 patients with COPD were recruited. CAT score showed a fair correlation with SGRQ score (r=0.429, P<0.001) and FEV1 (r=-0.231, P=0.02). Higher CAT score was significantly associated with more rapid decline of FEV1 over 2 years (P=0.02) and acute exacerbation of COPD (P=0.002)Conclusion: CAT score showed good relationship with various clinical parameters of COPD, including FEV1, acute exacerbation and deterioration of lung function. These findings suggest that CAT reflects various features of COPD and could be used more widely in assessing and monitoring of COPD.