RT Journal Article SR Electronic T1 Comparison of quality of life scores with modified Medical Research Council (mMRC) dyspnoea scale using data from the European health-related quality of life study JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P3219 VO 40 IS Suppl 56 A1 Paul Jones A1 Lukasz Adamek A1 Gilbert Nadeau A1 Norbert Banik YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P3219.abstract AB The 2011 Global Initiative for chronic obstructive lung disease (GOLD) guidelines recommend a combined assessment for measuring the impact of COPD which considers current symptoms and future exacerbation risk. Two symptom cut-points are proposed using the COPD Assessment Test (CAT) score ≥10 and modified Medical Research Council (mMRC) dyspnoea score ≥2. There are currently no published data comparing CAT scores by different mMRC grades.This analysis examined health status scores for CAT, St George's Respiratory Questionnaire (SGRQ) and short form health survey (SF-12) Physical Component (PC) split by mMRC grade in a primary care population using data from the Health-Related Quality of Life in European COPD Study.Data from 1817 patients (mean [SD] FEV1 1.6 [0.6] L; age 64.9 [9.6] years; males 72%) were used. The CAT, SGRQ and SF-12 PC scores are tabulated.The mMRC showed a clear relationship with scores from the comprehensive generic and disease-specific measures. mMRC Grade 1 was associated with very significant levels of health status impairment. Even the patients with mMRC Grade 0 had modestly elevated CAT and SGRQ scores, which means that mMRC Grade 0 does not mean the absence of symptoms.