RT Journal Article SR Electronic T1 Oral health and some risk factors in children with cystic fibrosis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P3382 VO 40 IS Suppl 56 A1 Seda Mete A1 Yasemin Gokdemir A1 Sertac Peker A1 Bulent Karadag A1 Betul Kargul YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P3382.abstract AB Cystic fibrosis (CF) is one of the most common genetic diseases worldwide. Previous studies on patients with CF have reported variable dental caries prevalence and physicochemical properties of saliva. The aim of this study was to investigate prevalence of dental caries and the relation with treatment, salivary flow rate, buffering capacity in children with CF compared with healthy peers.A cross-sectional observational survey was undertaken in children attending outpatient clinic. Study population included 30 children with CF (mean age 10.2±4.8 years), compared with a control group of 30 healthy children (mean age 9.9±1.4 years). Mean saliva pH was 7.25±0.45 for CF children and 7.45±0.34 for control (p=0.57). Mean salivary flow rate of the CF children was 1.30±0.7ml⁄min. and 1.54±0.9 ml⁄min for the control group (p=0.09). And the mean buffering capacity was 8.47±2.7 for CF children and 8.20±1.58 for control (p=0.64). Among the group of children with CF, with 23% of children being caries free. DMFT (Decay Missing Filled Teeth) was 4.6±4.0 in CF children and 7.7±2.7 in control children (p=0.001). Of all CF children, 60% CF brush their teeth once a day. Most of CF children 26(86%) start to brush teeth after 2 years of age.Although CF is a serious systemic chronic disease of childhood, buffering capacity of saliva seems to be higher than control group. Related to this characteristic of saliva, DMFT score of CF children were found to be lower than healthy group.