RT Journal Article SR Electronic T1 Menstrual status in women and sleep-related outcomes JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP P1880 VO 40 IS Suppl 56 A1 Francisco Gomez Real A1 Ferenc Macsali A1 Cecilie Svanes A1 Ernst Omenaas A1 Eva Lindberg A1 Karl Franklin A1 Bryndis Benediktsdottir A1 Thorarin Gislasson A1 Ane Johannessen A1 Vivi Schlunssen A1 Christer Janson A1 Mathias Holm A1 Rain Jogi YR 2012 UL http://erj.ersjournals.com/content/40/Suppl_56/P1880.abstract AB Background: There is limited knowledge about how menstrual status may influence sleep related outcomes. We aimed to investigate whether irregular menstruation and menopause affect sleep related symptoms including insomnia and gastroesophageal reflux,Methods: A population-based sample of 8588 women aged 25-55 years answering the Respiratory Health In Northern Europe (RHINE) postal questionnaire were analyzed. Logistic regression models were adjusted for BMI, age, smoking history and socioeconomic status.Results: Women reporting irregular menstruations had significantly more sleep-related symptoms (reflux after going to bed OR=1.67 [1.30 - 2.15], difficulty falling asleep (DIS) 1.42 [1.11 - 1.80], difficulty maintaining sleep (DMS) 1.44 [1.23 - 1.70], excessive daytime sleepiness (EDS) 1.27 [1.08 - 1.48] and early morning awakening (EMA) 1.45 [1.15 - 1.82]) than women menstruating regularly. Menopausal women had significantly higher risk of sleep-related symptoms (reflux after going to bed OR=1.43 [1.07 - 1.90], DIS 2.04 [1.58 - 2.63], DMS 1.87 [1.57 – 2.23], EDS 1.44 [1.21 - 1.73] and EMA 1.73 [1.38 - 2.17]) than premenopausal women.Conclusions: Sleep quality among women was significantly related to menstrual status; women with irregular menstruations and menopausal women suffered from more sleep-related symptoms with insomnia and gastroesophageal reflux.